发明公开
EP2283130A4 DISPERSINBtm, 5-FLUOROURACIL, DEOXYRIBONUCLEASE I AND PROTEINASE K-BASED ANTIBIOFILM COMPOSITIONS AND USES THEREOF
有权
ON DISPERSINBTM，5-氟尿嘧啶，脱氧核糖核酸酶I和蛋白酶K类抗生物膜组合物及其应用
- 专利标题： DISPERSINBtm, 5-FLUOROURACIL, DEOXYRIBONUCLEASE I AND PROTEINASE K-BASED ANTIBIOFILM COMPOSITIONS AND USES THEREOF
- 专利标题（中）： ON DISPERSINBTM，5-氟尿嘧啶，脱氧核糖核酸酶I和蛋白酶K类抗生物膜组合物及其应用
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申请号： EP09726733申请日： 2009-04-03
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公开(公告)号： EP2283130A4公开(公告)日： 2012-10-10
- 发明人: MADHYASTHA SRINIVASA , GAWANDE PURUSHOTTAM , LOVETRI KAREN , YAKANDAWALA NANDADEVA , KAPLAN JEFFREY B
- 申请人： KANE BIOTECH INC
- 专利权人： KANE BIOTECH INC
- 当前专利权人： KANE BIOTECH INC
- 优先权： US4194108 2008-04-03
- 主分类号： C12N9/58
- IPC分类号： C12N9/58 ; A61K31/513 ; A61K38/46 ; A61K38/47 ; A61K38/48 ; A61L15/38 ; A61L15/46 ; A61L27/54 ; A61L29/16 ; A61L31/16 ; A61P1/02 ; A61P17/02 ; A61P31/00 ; B05D1/02 ; C12N9/00 ; C12N9/22 ; C12N9/24
摘要：
The present invention provides antibiofilm composition comprising two or more agents selected from the group consisting of DispersinB(TM), 5-Fluorouracil, Deoxyribonuclease I and Proteinase K for preventing growth and proliferation of biofilm-embedded microorganisms in wound care, oral care, and disease-related infections and methods of treatment in mammals. The invention further provides methods for preparing medical devices, and wound care devices using an antibiofilm composition comprising two or more antimicrobial agents selected from the group consisting of DispersinB(TM), 5-Fluorouracil, Deoxyribonuclease I and Proteinase K.
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