发明公开
- 专利标题： IMMUNOMODULATION BY IAP INHIBITORS
- 专利标题（中）： 免疫调节麻醉剂IAP-INHIBITOREN
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申请号： EP09747530.5申请日： 2009-05-14
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公开(公告)号： EP2296650A1公开(公告)日： 2011-03-23
- 发明人: ZAWEL, Leigh , DRANOFF, Glenn , DOUGAN, Michael , STRAUB, Christopher, S. , FIRESTONE, Brant, G.
- 申请人： Novartis AG , Dana Farber Cancer Institute, Inc.
- 申请人地址： Lichtstrasse 35 4056 Basel CH
- 专利权人： Novartis AG,Dana Farber Cancer Institute, Inc.
- 当前专利权人： Novartis AG,Dana Farber Cancer Institute, Inc.
- 当前专利权人地址： Lichtstrasse 35 4056 Basel CH
- 代理机构： Clyde-Watson, Zöe
- 优先权： US53947 20080516
- 国际公布： WO2009140447 20091119
- 主分类号： A61K31/437
- IPC分类号： A61K31/437
摘要：
The present invention is directed to immune adjuvants containing IAP inhibitors, including Smac mimetics. The invention further provides pharmaceutical compositions and vaccines containing an IAP inhibitor and an antigen. Methods of enhancing an immune response by administration of an IAP inhibitor, methods of treating or preventing cancer, methods of treating or preventing infections, methods of treating autoimmune disorders, and methods of potentiating cytokine or antibody production are also provided.
公开/授权文献
- EP2296650B1 IMMUNOMODULATION BY IAP INHIBITORS 公开/授权日：2020-05-06
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