- 专利标题： Triazole compounds that modulate HSP90 activity
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申请号： EP10075452.2申请日： 2005-11-17
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公开(公告)号： EP2298748A2公开(公告)日： 2011-03-23
- 发明人: Ying, Weiwen , James, David , Zhang, Shijie , Przewloka, Teresa , Chae, Junghyun , Chimmanamada, Dinesh U , Lee, Chi-Wan , Kostik, Elena , Ng, Howard P , Foley, Kevin , Du, Zhenjian , Barsoum, James
- 申请人： Synta Pharmaceuticals Corp.
- 申请人地址： 45 Hartwell Avenue Lexington, MA 02421 US
- 专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人地址： 45 Hartwell Avenue Lexington, MA 02421 US
- 代理机构： Snodin, Michael D.
- 优先权： US628979P 20041118; US709358P 20050818; US725044P 20051006
- 主分类号： C07D249/12
- IPC分类号： C07D249/12 ; C07D401/04 ; C07D405/04 ; C07D403/04 ; A61K31/4196 ; A61P35/00
摘要：
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
公开/授权文献
- EP2298748B1 Triazole compounds that modulate HSP90 activity 公开/授权日：2016-07-20
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