发明公开
- 专利标题: CRKL TARGETING PEPTIDES
- 专利标题(中): 目标END CRKL肽
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申请号: EP09767865.0申请日: 2009-06-19
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公开(公告)号: EP2303913A2公开(公告)日: 2011-04-06
- 发明人: ARAP, Wadih , MINTZ, Paul, J. , PASQUALINI, Renata
- 申请人: The Board of Regents of The University of Texas System
- 申请人地址: 201 West 7th Street Austin, TX 78701 US
- 专利权人: The Board of Regents of The University of Texas System
- 当前专利权人: The Board of Regents of The University of Texas System
- 当前专利权人地址: 201 West 7th Street Austin, TX 78701 US
- 代理机构: Vossius & Partner
- 优先权: US74423P 20080620
- 国际公布: WO2009155556 20091223
- 主分类号: C07K7/08
- IPC分类号: C07K7/08 ; C07K7/06 ; A61K38/10 ; A61P35/00
摘要:
Provided are methods and compositions for selectively targeting CRKL through the use of targeting peptides. Selective targeting of secreted CRKL through the use of a targeting peptide may be used, for example, in the treatment of cancer to deliver a chemotherapeutic compound, fusion protein, or fusion construct to a cancer cell or tissue.
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