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公开(公告)号:EP3548131B1
公开(公告)日:2024-10-30
申请号:EP18842340.4
申请日:2018-07-27
发明人: KIM, Daniel H. , SHIN, Dong Suk , PALMRE, Viljar , SHIM, Younghee
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公开(公告)号:EP4393549A3
公开(公告)日:2024-10-09
申请号:EP24161024.5
申请日:2017-05-16
发明人: MILLER, Jason B. , JOHNSON, Arthur E. , THOMAS, Philip J. , TORRES, Michael J. , SIEGWART, Daniel J.
IPC分类号: A61K9/00 , A61K31/7125 , A61K47/20 , A61K47/22 , C07C321/14 , A61K9/51 , A61K31/7105 , A61K31/7088 , A61K9/127 , A61P27/04 , A61P35/00 , A61P43/00 , A61P39/02 , A61P25/08 , A61P21/04
CPC分类号: A61K9/127 , A61K9/5123 , A61K31/7088 , A61K31/7105 , A61K9/0019 , A61P21/04 , A61P25/08 , A61P35/00 , A61P39/02 , A61P43/00
摘要: In some aspects, the present disclosure provides a nanoparticle composition comprising tRNA and an aminolipid delivery compound. The aminolipid delivery compound may be a dendrimer, dendron, or dendritic lipid, a polymer such as a polyamide or polyester, or a lipid with one or more hydrophobic components. In some embodiments, these compositions may be administered to a patient to treat a genetic disease or disorder such as cystic fibrosis, Duchene muscular dystrophy, or cancer.
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公开(公告)号:EP4419935A1
公开(公告)日:2024-08-28
申请号:EP22884628.3
申请日:2022-10-18
发明人: BAI, Ti , BALAGOPAL, Anjali , NGUYEN, Dan , JIANG, Steve
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公开(公告)号:EP4362986A1
公开(公告)日:2024-05-08
申请号:EP22747202.4
申请日:2022-06-27
发明人: BAILEY, Rachel, M.
CPC分类号: C12N15/86 , C12N2750/1414320130101 , A61K48/005 , A61P25/28 , C12N15/113 , C12N2310/14120130101 , C12N2320/1120130101
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公开(公告)号:EP3630116B1
公开(公告)日:2024-05-01
申请号:EP18805888.7
申请日:2018-05-25
IPC分类号: C07D471/04 , C07D471/18 , A61K31/519 , A61P35/00
CPC分类号: A61P35/00 , C07D471/18 , C07D471/04
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公开(公告)号:EP3439667B1
公开(公告)日:2024-01-03
申请号:EP17779694.3
申请日:2017-04-04
发明人: ZHONG, Boyu , SUN, Lijun , SHI, Heping , LI, Jing , CHEN, Chuo , CHEN, Zhijian
IPC分类号: A61K31/665 , A61K39/39 , C07D417/14 , A61P35/00
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公开(公告)号:EP3716869B1
公开(公告)日:2023-11-01
申请号:EP18897369.7
申请日:2018-12-20
发明人: KIM, Daniel H. , SHIN, Dong Suk , JANG, Taeho , PARK, Yongman , LEE, Jeihan , KIM, Hongmin , NAM, Kihoon , HAN, Seokyung
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公开(公告)号:EP3849608B1
公开(公告)日:2023-08-30
申请号:EP19860440.7
申请日:2019-09-12
发明人: AN, Zhiqiang , ZHANG, Chengcheng , ZHANG, Ningyan , GUI, Xun , DENG, Mi , HUANG, Tao , LIU, Qiang , LIAO, X. Charlene
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公开(公告)号:EP3027764B1
公开(公告)日:2022-10-12
申请号:EP14832076.5
申请日:2014-07-31
IPC分类号: C12Q1/06 , G01N27/02 , G01N27/327
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