发明公开
- 专利标题: DIAGNOSTIC AGENTS SELECTIVE AGAINST METALLOPROTEASES
- 专利标题(中): 对金属蛋白酶选择性的诊断试剂
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申请号: EP09800042.5申请日: 2009-07-21
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公开(公告)号: EP2320954A1公开(公告)日: 2011-05-18
- 发明人: ROSSELLO, Armando , NUTI, Elisa , AVRAMOVA, Stanislava Ivanova , UGGERI, Fulvio , MAIOCCHI, Alessandro
- 申请人: Bracco Imaging S.p.A
- 申请人地址: Via Egidio Folli 50 20134 Milano IT
- 专利权人: Bracco Imaging S.p.A
- 当前专利权人: Bracco Imaging S.p.A
- 当前专利权人地址: Via Egidio Folli 50 20134 Milano IT
- 代理机构: Merli, Silvia
- 优先权: EP08160856 20080722
- 国际公布: WO2010010079 20100128
- 主分类号: A61K49/00
- IPC分类号: A61K49/00 ; A61K49/10 ; A61K49/22 ; A61K51/04 ; A61P43/00 ; C07C311/48 ; C07D295/08 ; C07D295/088
摘要:
The invention relates to aryl-sulphonamido compounds endowed with affinity against metallo proteases MMP, having formula (I) below wherein R, R 1 , R 2 , R 3 , G and n have the meanings reported in the specification, properly labelled with diagnostic imaging moieties or even radiotherapeutic moieties. The invention also refers to the process for their preparation, to pharmaceutical compositions comprising them and to their use as diagnostic imaging agents or radiotherapeutic agents.
公开/授权文献
- EP2320954B1 DIAGNOSTIC AGENTS SELECTIVE AGAINST METALLOPROTEASES 公开/授权日:2019-09-04
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