发明公开
- 专利标题: ORGANIC COMPOUNDS
- 专利标题(中): 有机化合物
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申请号: EP09810900.2申请日: 2009-08-17
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公开(公告)号: EP2321272A1公开(公告)日: 2011-05-18
- 发明人: MANG, Rosemarie , HEILMAYER, Werner
- 申请人: Nabriva Therapeutics AG
- 申请人地址: Leberstrasse 20 1112 Wien AT
- 专利权人: Nabriva Therapeutics AG
- 当前专利权人: Nabriva Therapeutics AG
- 当前专利权人地址: Leberstrasse 20 1112 Wien AT
- 代理机构: Schwarz, Albin
- 优先权: EP08450126 20080902
- 国际公布: WO2010025482 20100311
- 主分类号: C07C323/52
- IPC分类号: C07C323/52 ; C07D211/60 ; A61K31/215 ; A61K31/4458 ; A61P31/04
摘要:
Compounds of formula (I), which are 14-
O -{[(optionally substituted hydroxy)cyclohexyl)sulfanyl]acetyl}mutilins further substituted at the cyclohexyl group by an acylated amino group, salts and solvates thereof, pharmaceutical compositions comprising such compounds and their use as a pharmaceutical,
e.g. for the treatment of diseases mediated by microbes and for the treatment of inflammation where microbese are mediating said inflammation.
O -{[(optionally substituted hydroxy)cyclohexyl)sulfanyl]acetyl}mutilins further substituted at the cyclohexyl group by an acylated amino group, salts and solvates thereof, pharmaceutical compositions comprising such compounds and their use as a pharmaceutical,
e.g. for the treatment of diseases mediated by microbes and for the treatment of inflammation where microbese are mediating said inflammation.
公开/授权文献
- EP2321272B1 ORGANIC COMPOUNDS 公开/授权日:2016-04-20
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