发明公开
- 专利标题: PYRIDONS AS PDK1 INHIBITORS
- 专利标题(中): 吡啶酮ALS抑制剂PDK1
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申请号: EP09780675.6申请日: 2009-07-15
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公开(公告)号: EP2321299A2公开(公告)日: 2011-05-18
- 发明人: ENGELHARDT, Harald , BOEHMELT, Guido , KOFINK, Christiane , KUHN, Daniel , MCCONNELL, Darryl , STADTMUELLER, Heinz
- 申请人: Boehringer Ingelheim International GmbH
- 申请人地址: Binger Strasse 173 55216 Ingelheim am Rhein DE
- 专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人地址: Binger Strasse 173 55216 Ingelheim am Rhein DE
- 代理机构: Hammann, Heinz
- 优先权: EP08160567 20080716; EP09160842 20090520
- 国际公布: WO2010007116 20100121
- 主分类号: C07D401/12
- IPC分类号: C07D401/12 ; C07D401/04 ; C07D401/14 ; C07D487/04 ; A61K31/435 ; A61P35/00
摘要:
The present invention encompasses compounds of general formula (1) while the groups R
4 to R
7 and the units W, L, Q
a and Q
H are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and their use as medicaments having the above-mentioned properties.
4 to R
7 and the units W, L, Q
a and Q
H are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and their use as medicaments having the above-mentioned properties.
公开/授权文献
- EP2321299B1 PYRIDONS AS PDK1 INHIBITORS 公开/授权日:2016-02-24
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