发明公开
EP2331118A1 COMPOSITION OF TUMOR-ASSOCIATED PEPTIDES AND RELATED ANTI-CANCER VACCINE FOR THE TREATMENT OF GLIOBLASTOMA (GBM) AND OTHER CANCERS
有权
肿瘤相关肽和相关抗癌疫苗的组合用于治疗脑胶质瘤（GBM）和其他癌症
- 专利标题： COMPOSITION OF TUMOR-ASSOCIATED PEPTIDES AND RELATED ANTI-CANCER VACCINE FOR THE TREATMENT OF GLIOBLASTOMA (GBM) AND OTHER CANCERS
- 专利标题（中）： 肿瘤相关肽和相关抗癌疫苗的组合用于治疗脑胶质瘤（GBM）和其他癌症
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申请号： EP09778749.3申请日： 2009-09-28
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公开(公告)号： EP2331118A1公开(公告)日： 2011-06-15
- 发明人: SCHOOR, Oliver , HILF, Norbert , WEINSCHENK, Toni , TRAUTWEIN, Claudia , WALTER, Steffen , SINGH, Harpreet
- 申请人： Immatics Biotechnologies GmbH
- 申请人地址： Paul-Ehrlich-Strasse 15 72076 Tübingen DE
- 专利权人： Immatics Biotechnologies GmbH
- 当前专利权人： Immatics Biotechnologies GmbH
- 当前专利权人地址： Paul-Ehrlich-Strasse 15 72076 Tübingen DE
- 代理机构： Krauss, Jan
- 优先权： EP08017305 20081001; US105970P 20081016
- 国际公布： WO2010037513 20100408
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61P35/00 ; A61K38/08 ; A61K38/16
摘要：
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 25 novel peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
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