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公开(公告)号：EP3120869B1
公开(公告)日：2020-07-22
申请号：EP16179192.6
申请日：2009-09-28
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公开(公告)号：EP3111952B1
公开(公告)日：2018-10-31
申请号：EP16179241.1
申请日：2009-09-28
发明人： SCHOOR, Oliver , HILF, Norbert , WEINSCHENK, Toni , TRAUTWEIN, Claudia , WALTER, Steffen , SINGH, Harpreet
CPC分类号： C07K7/06 , A61K35/17 , A61K38/00 , A61K39/0011 , A61K2039/5154 , A61K2039/5158 , A61K2039/53 , A61K2039/55511 , A61K2039/55516 , A61K2039/55522 , A61K2039/55561 , A61K2039/55588 , A61K2039/572 , A61K2039/605 , A61K2039/6081 , A61K2039/6093 , A61M5/002 , C07K7/08 , C07K14/70539 , C07K2319/00 , C07K2319/40 , C12N5/0638 , C12N2501/50 , G01N33/57492 , Y02A50/472
摘要： The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 25 novel peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
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3.发明公开NOVEL IMMUNOTHERAPY AGAINST SEVERAL TUMORS INCLUDING NEURONAL AND BRAIN TUMORS 审中-公开新型免疫疗法针对不同肿瘤，包括神经和脑肿瘤
公开(公告)号：EP3124043A1
公开(公告)日：2017-02-01
申请号：EP16179214.8
申请日：2009-09-28
发明人： SCHOOR, Oliver , HILF, Norbert , WEINSCHENK, Toni , TRAUTWEIN, Claudia , WALTER, Steffen , SINGH, Harpreet
CPC分类号： A61K39/0011 , A61K35/17 , A61K38/00 , A61K2039/5154 , A61K2039/5158 , A61K2039/53 , A61K2039/55511 , A61K2039/55516 , A61K2039/55522 , A61K2039/55561 , A61K2039/55588 , A61K2039/572 , A61K2039/605 , A61K2039/6081 , A61K2039/6093 , A61M5/002 , C07K7/06 , C07K7/08 , C07K14/70539 , C07K2319/00 , C07K2319/40 , C12N5/0638 , C12N2501/50 , G01N33/57492 , Y02A50/472
摘要： The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 30 peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
摘要翻译： 本发明涉及肽，核酸和细胞免疫治疗方法中使用。 特别地，本发明涉及癌症的免疫疗法。 本发明进一步更涉及肿瘤相关细胞毒性T细胞（CTL）肽表位，单独或与其它肿瘤相关肽组合并用作疫苗组合物的活性药物成分并刺激抗肿瘤免疫应答。 本发明涉及并能在疫苗组合物可用于引发抗肿瘤免疫应答从HLA I类和人肿瘤细胞的II分子衍生的30个肽序列及其变体。
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公开(公告)号：EP2183361A1
公开(公告)日：2010-05-12
申请号：EP08785107.7
申请日：2008-07-25
发明人： SCHOOR, Oliver , HILF, Norbert , WEINSCHENK, Toni , TRAUTWEIN, Claudia , WALTER, Steffen , SINGH, Harpreet
CPC分类号： A61K35/17 , A61K38/00 , C07K7/06 , C07K7/08 , C07K14/4748 , C12N5/0638
摘要： The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 11 novel peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-rumor immune responses.
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公开(公告)号：EP3120868B1
公开(公告)日：2020-04-08
申请号：EP16179174.4
申请日：2009-09-28
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公开(公告)号：EP3120870B1
公开(公告)日：2020-04-01
申请号：EP16179226.2
申请日：2009-09-28
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公开(公告)号：EP3132801B1
公开(公告)日：2019-10-30
申请号：EP16179169.4
申请日：2009-09-28
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8.发明公开COMPOSITION OF TUMOUR-ASSOCIATED PEPTIDES AND RELATED ANTI-CANCER VACCINE 有权ZUSAMMENSETZUNG VON TUMORASSOZIIERTEN PEPTIDEN UND VERWANDTER IMPFSTOFF GEGEN KREBS
公开(公告)号：EP2178557A1
公开(公告)日：2010-04-28
申请号：EP08785105.1
申请日：2008-07-25
发明人： SINGH, Harpreet , SCHOOR, Oliver , TRAUTWEIN, Claudia , HILF, Norbert , WEINSCHENK, Toni , WALTER, Steffen , LEWANDROWSKI, Peter
CPC分类号： A61K39/0011 , A61K38/193 , A61K45/06 , A61K2039/5158 , A61K2039/53 , A61K2039/572 , C07K14/4748 , A61K2300/00
摘要： The present invention relates to immunotherapeutic peptides and their use in immunotherapy, in particular the immunotherapy of cancer. The present invention discloses tumour-associated T-helper cell peptide epitopes, alone or in combination with other tumour-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumour immune responses. In particular, the composition of the peptides of the present invention can be used in vaccine compositions for eliciting anti-tumour immune responses against colorectal cancer.
摘要翻译： 本发明涉及免疫治疗肽及其在免疫治疗中的用途，特别是癌症的免疫治疗。 本发明公开了肿瘤相关的T辅助细胞肽表位，其单独或与作为刺激抗肿瘤免疫应答的疫苗组合物的活性药物成分的其它肿瘤相关肽组合。 特别地，本发明的肽的组合物可用于引发针对结肠直肠癌的抗肿瘤免疫应答的疫苗组合物中。
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9.发明授权
公开(公告)号：EP2178557B1
公开(公告)日：2017-03-01
申请号：EP08785105.1
申请日：2008-07-25
发明人： SINGH, Harpreet , SCHOOR, Oliver , TRAUTWEIN, Claudia , HILF, Norbert , WEINSCHENK, Toni , WALTER, Steffen , LEWANDROWSKI, Peter
CPC分类号： A61K39/0011 , A61K38/193 , A61K45/06 , A61K2039/5158 , A61K2039/53 , A61K2039/572 , C07K14/4748 , A61K2300/00
摘要： The present invention relates to immunotherapeutic peptides and their use in immunotherapy, in particular the immunotherapy of cancer. The present invention discloses tumour-associated T-helper cell peptide epitopes, alone or in combination with other tumour-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumour immune responses. In particular, the composition of the peptides of the present invention can be used in vaccine compositions for eliciting anti-tumour immune responses against colorectal cancer.
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10.发明公开NOVEL IMMUNOTHERAPY AGAINST SEVERAL TUMORS INCLUDING NEURONAL AND BRAIN TUMORS 审中-公开新型免疫疗法针对不同肿瘤，包括神经和脑肿瘤
公开(公告)号：EP3120869A1
公开(公告)日：2017-01-25
申请号：EP16179192.6
申请日：2009-09-28
发明人： SCHOOR, Oliver , HILF, Norbert , WEINSCHENK, Toni , TRAUTWEIN, Claudia , WALTER, Steffen , SINGH, Harpreet
摘要： The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 30 peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
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