发明公开
EP2332541A1 Use of thioxanthine derivatives as MPO inhibitors
审中-公开
Verwendung von Thioxanthinderivaten als MPO Hemmer
- 专利标题： Use of thioxanthine derivatives as MPO inhibitors
- 专利标题（中）： Verwendung von Thioxanthinderivaten als MPO Hemmer
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申请号： EP10170768.5申请日： 2003-04-15
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公开(公告)号： EP2332541A1公开(公告)日： 2011-06-15
- 发明人: HANSON, Sverker , NORDVALL, Gunnar , TIDÉN, Anna-Karin
- 申请人： AstraZeneca AB
- 申请人地址： 151 85 Södertälje SE
- 专利权人： AstraZeneca AB
- 当前专利权人： AstraZeneca AB
- 当前专利权人地址： 151 85 Södertälje SE
- 优先权： SE0201193 20020419; SE0202239 20020717
- 主分类号： A61K31/522
- IPC分类号： A61K31/522 ; C07D473/22
摘要：
A compound of formula (Ia) or (Ib)
wherein X is S; Y is O; R 2 is C1 to 6 alkyl substituted by C1 to 6 alkoxy; and R 1 R 3 and R 4 are all hydrogen, or a pharmaceutically acceptable salt thereof, the preparation of such compounds, compositions comprising such compounds, and the use of such compounds in the treatment of MPO mediated disease states.
wherein X is S; Y is O; R 2 is C1 to 6 alkyl substituted by C1 to 6 alkoxy; and R 1 R 3 and R 4 are all hydrogen, or a pharmaceutically acceptable salt thereof, the preparation of such compounds, compositions comprising such compounds, and the use of such compounds in the treatment of MPO mediated disease states.
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