发明公开
- 专利标题: POLYMER CONJUGATES OF OSTEOCALCIN PEPTIDES
- 专利标题(中): 骨钙素肽的聚合物缀合物
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申请号: EP09789332.5申请日: 2009-09-17
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公开(公告)号: EP2334336A1公开(公告)日: 2011-06-22
- 发明人: ROCZNIAK, Steven O. , ALI, Cherie F.
- 申请人: Nektar Therapeutics
- 申请人地址: 455 Mission Bay Boulevard South, Suite 100 San Francisco, CA 94185 US
- 专利权人: Nektar Therapeutics
- 当前专利权人: Nektar Therapeutics
- 当前专利权人地址: 455 Mission Bay Boulevard South, Suite 100 San Francisco, CA 94185 US
- 代理机构: Baldock, Sharon Claire
- 优先权: US192672P 20080919; US208089P 20090218; US153960P 20090219
- 国际公布: WO2010033218 20100325
- 主分类号: A61K47/48
- IPC分类号: A61K47/48 ; C07K14/575
摘要:
The invention provides osteocalcin that is chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the peptide not attached to the water-soluble oligomer.
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