发明公开
EP2336777A1 Serum bactericidal assay for N. meningitidis specific antisera
有权
Bakterizidie-SerumtestfürN. Meningitidis spezifische Antiseren
- 专利标题： Serum bactericidal assay for N. meningitidis specific antisera
- 专利标题（中）： Bakterizidie-SerumtestfürN. Meningitidis spezifische Antiseren
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申请号： EP10179015.2申请日： 2005-09-05
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公开(公告)号： EP2336777A1公开(公告)日： 2011-06-22
- 发明人: De Vleeschauwer, Isabel , Durant, Nathalie , Poolman, Jan , Weynants, Vincent
- 申请人： GlaxoSmithKline Biologicals s.a.
- 申请人地址： rue de l'Institut 89 1330 Rixensart BE
- 专利权人： GlaxoSmithKline Biologicals s.a.
- 当前专利权人： GlaxoSmithKline Biologicals s.a.
- 当前专利权人地址： rue de l'Institut 89 1330 Rixensart BE
- 代理机构： Johnston, Caroline Louise
- 主分类号： G01N33/569
- IPC分类号： G01N33/569 ; C12N1/22
摘要：
The present invention relates to the field of Serum Bactericidal Activity (SBA) assays for Gram negative bacteria, in particular N. meningitidis. The SBA assay is the most important method for measuring functional activity of serum antibodies against meningococcus. In order to determine whether a subject or a population is seropositive against invasive meningococcus the SBA test should ideally be both sensitive and specific. The inventors have found the standard N. meningitidis serotype A and W SBAs can be significantly improved in this regard.
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