发明授权
EP2337846B1 NON-NATURAL AMINO ACID REPLICATION-DEPENDENT MICROORGANISMS AND VACCINES
有权
非天然氨基酸复制依赖性微生物和疫苗
- 专利标题: NON-NATURAL AMINO ACID REPLICATION-DEPENDENT MICROORGANISMS AND VACCINES
- 专利标题(中): 非天然氨基酸复制依赖性微生物和疫苗
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申请号: EP09817017.8申请日: 2009-09-28
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公开(公告)号: EP2337846B1公开(公告)日: 2018-01-17
- 发明人: TIAN, Feng , HEHLI, Brad
- 申请人: Ambrx, Inc.
- 申请人地址: 10975 North Torrey Pines Road, Suite 100 La Jolla, CA 92037 US
- 专利权人: Ambrx, Inc.
- 当前专利权人: Ambrx, Inc.
- 当前专利权人地址: 10975 North Torrey Pines Road, Suite 100 La Jolla, CA 92037 US
- 代理机构: Alexander, Sean Matthew
- 优先权: US100688P 20080926
- 国际公布: WO2010037062 20100401
- 主分类号: C12N1/36
- IPC分类号: C12N1/36 ; C12P21/00 ; C12N9/00 ; A61K39/108 ; C12N15/70
摘要:
Compositions and methods of producing vaccines, including methods wherein whole organism vaccines are provided with limited replication abilities, thereby increasing vaccine safety and efficacy, through the use of non-natural, unnatural, or non-naturally encoded amino acids.
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