发明公开
EP2344187A1 TARGETING OF ANTIGEN PRESENTING CELLS WITH IMMUNONANOTHERAPEUTICS
有权
ZIENEN VON ANTIGENPRÄSENTIERENDENZELLEN MIT IMMUNONANOTHERAPEUTIKA
- 专利标题： TARGETING OF ANTIGEN PRESENTING CELLS WITH IMMUNONANOTHERAPEUTICS
- 专利标题（中）： ZIENEN VON ANTIGENPRÄSENTIERENDENZELLEN MIT IMMUNONANOTHERAPEUTIKA
-
申请号： EP09740582.3申请日： 2009-10-09
-
公开(公告)号： EP2344187A1公开(公告)日： 2011-07-20
- 发明人: SHI, Jinjun , ALEXIS, Frank , IANNACONE, Matteo , MOSEMAN, Ashley , BASTO, Pamela , LANGER, Robert , FAROKHZAD, Omid, C. , VON ANDRIAN, Ulrich , TONTI, Elena
- 申请人： Massachusetts Institute of Technology , President and Fellows of Harvard College , The Brigham and Women's Hospital, Inc.
- 申请人地址： 77 Massachusetts Avenue Cambridge, MA 02139 US
- 专利权人： Massachusetts Institute of Technology,President and Fellows of Harvard College,The Brigham and Women's Hospital, Inc.
- 当前专利权人： Massachusetts Institute of Technology,President and Fellows of Harvard College,The Brigham and Women's Hospital, Inc.
- 当前专利权人地址： 77 Massachusetts Avenue Cambridge, MA 02139 US
- 代理机构： Bassett, Richard Simon
- 优先权： PCT/US2008/001193 20081012; US428381 20090422
- 国际公布： WO2010042876 20100415
- 主分类号： A61K39/00
- IPC分类号： A61K39/00
摘要：
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface. The nanocarriers are capable of targeting antigen presenting cells when administered to a subject. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof.
公开/授权文献
信息查询
