发明公开
EP2350030A1 ISOXAZOLE/ISOXAZOLINE/COMBRETASTATIN LINKED DIHYDROQUINAZOLINONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF
有权
HYBRID彼此相关联公司及DIHYDROQUINAZOLINON异恶唑，异恶唑啉或考布他汀作为生产可能的抗癌药物和方法
- 专利标题： ISOXAZOLE/ISOXAZOLINE/COMBRETASTATIN LINKED DIHYDROQUINAZOLINONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF
- 专利标题（中）： HYBRID彼此相关联公司及DIHYDROQUINAZOLINON异恶唑，异恶唑啉或考布他汀作为生产可能的抗癌药物和方法
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申请号： EP09749198.9申请日： 2009-09-08
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公开(公告)号： EP2350030A1公开(公告)日： 2011-08-03
- 发明人: KAMAL, Ahmed , BHARATHI, Earla, Vijaya , REDDY, Jonnala, Surendranadha , DASTAGIRI, Dudekula , VISWANATH, Arutla
- 申请人： Council Of Scientific & Industrial Research
- 申请人地址： Anusandhan of Societies Act (Act XXI of 1860) Anusandhan Bhawan 2 Rafi Marg. New Delhi 110 001 IN
- 专利权人： Council Of Scientific & Industrial Research
- 当前专利权人： Council Of Scientific & Industrial Research
- 当前专利权人地址： Anusandhan of Societies Act (Act XXI of 1860) Anusandhan Bhawan 2 Rafi Marg. New Delhi 110 001 IN
- 代理机构： Jönsson, Anneli
- 优先权： INDE26022008 20081119
- 国际公布： WO2010058417 20100527
- 主分类号： C07D239/91
- IPC分类号： C07D239/91 ; C07D413/12 ; A61K31/422 ; A61K31/517 ; A61P35/00
摘要：
The present invention provides a compound of general formulae 3a-i to 6a-i, 7a-i to 10a- i, 12a-i to 15a-i, 16a-i to 19a-i, 21a-i to 24a-i, 25a-i to 28a-i, 30a-i to 33a-i, 34a-i to37a-i and 39a-i to 42a-i, 43a-i to 46a-i useful as potential antitumour agents against human cancer cell lines and a process for the preparation thereof.
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