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1.发明授权ISOXAZOLE/ISOXAZOLINE/COMBRETASTATIN LINKED DIHYDROQUINAZOLINONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF 有权HYBRID彼此相关联公司及DIHYDROQUINAZOLINON异恶唑，异恶唑啉或考布他汀作为生产可能的抗癌药物和方法
公开(公告)号：EP2350030B9
公开(公告)日：2016-10-26
申请号：EP09749198.9
申请日：2009-09-08
发明人： KAMAL, Ahmed , BHARATHI, Earla, Vijaya , REDDY, Jonnala, Surendranadha , DASTAGIRI, Dudekula , VISWANATH, Arutla
IPC分类号： C07D239/91 , C07D413/12 , A61K31/422 , A61K31/517 , A61P35/00
CPC分类号： C07D239/91 , C07D413/12
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2.发明授权ISOXAZOLE/ISOXAZOLINE/COMBRETASTATIN LINKED DIHYDROQUINAZOLINONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF 有权异恶唑/异恶唑啉/苄嘧磺胺结合的二氢喹唑啉酮混合物作为潜在的抗癌剂及其制备方法
公开(公告)号：EP2350030B1
公开(公告)日：2016-04-20
申请号：EP09749198.9
申请日：2009-09-08
发明人： KAMAL, Ahmed , BHARATHI, Earla, Vijaya , REDDY, Jonnala, Surendranadha , DASTAGIRI, Dudekula , VISWANATH, Arutla
IPC分类号： C07D239/91 , C07D413/12 , A61K31/422 , A61K31/517 , A61P35/00
CPC分类号： C07D239/91 , C07D413/12
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3.发明授权ISOXAZOLINE LINKED PYRROLO [2,1-C][1,4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND THE PROCESS FOR PREPARATTION THEREOF 有权异恶唑啉LINKED吡咯并[2,1-C] [1,4] BENZODIAZEPINHYBRIDE作为潜在抗癌剂和PROCESS FOR THEIR
公开(公告)号：EP2271648B1
公开(公告)日：2013-02-13
申请号：EP08873662.4
申请日：2008-10-31
IPC分类号： C07D487/04 , A61K31/5517 , A61P35/00
CPC分类号： C07D487/04
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4.发明公开ISOXAZOLE/ISOXAZOLINE/COMBRETASTATIN LINKED DIHYDROQUINAZOLINONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF 有权HYBRID彼此相关联公司及DIHYDROQUINAZOLINON异恶唑，异恶唑啉或考布他汀作为生产可能的抗癌药物和方法
公开(公告)号：EP2350030A1
公开(公告)日：2011-08-03
申请号：EP09749198.9
申请日：2009-09-08
发明人： KAMAL, Ahmed , BHARATHI, Earla, Vijaya , REDDY, Jonnala, Surendranadha , DASTAGIRI, Dudekula , VISWANATH, Arutla
IPC分类号： C07D239/91 , C07D413/12 , A61K31/422 , A61K31/517 , A61P35/00
CPC分类号： C07D239/91 , C07D413/12
摘要： The present invention provides a compound of general formulae 3a-i to 6a-i, 7a-i to 10a- i, 12a-i to 15a-i, 16a-i to 19a-i, 21a-i to 24a-i, 25a-i to 28a-i, 30a-i to 33a-i, 34a-i to37a-i and 39a-i to 42a-i, 43a-i to 46a-i useful as potential antitumour agents against human cancer cell lines and a process for the preparation thereof.
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5.发明授权QUINAZOLINONE LINKED PYRROLO[2,1 -C][1.4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FORTHE PREPARATION THEREOF 有权喹唑啉酮连接的吡咯并[2,1-C] [1.4]苯并二氮杂作为潜在的抗癌剂及其制备方法
公开(公告)号：EP2350085B1
公开(公告)日：2013-06-19
申请号：EP09787601.5
申请日：2009-07-13
发明人： KAMAL, Ahmed , BHARATHI, Earla, Vijaya , DASTAGIRI, Dudekula , REDDY, Jonnala, Surendranadha , VISWANATH, Aruthla
IPC分类号： C07D487/04 , A61K31/5517 , A61P35/00
CPC分类号： C07D487/04
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6.发明公开QUINAZOLINONE LINKED PYRROLOÝ2,1 -C¨Ý1.4¨BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FORTHE PREPARATION THEREOF 有权喹唑酮连接的吡咯并[2,1-C] -1,4-苯并二氮杂化合物作为潜在的抗癌剂及其制备方法
公开(公告)号：EP2350085A1
公开(公告)日：2011-08-03
申请号：EP09787601.5
申请日：2009-07-13
发明人： KAMAL, Ahmed , BHARATHI, Earla, Vijaya , DASTAGIRI, Dudekula , REDDY, Jonnala, Surendranadha , VISWANATH, Aruthla
IPC分类号： C07D487/04 , A61K31/5517 , A61P35/00
CPC分类号： C07D487/04
摘要： The present invention provides a compound of general formulae 5a-r, 9a-i to 13a-i and 17a-i to 22a-i, useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1- c][1,4]benzodiazepine hybrids of general formulae 5a-r, 9a-i to 13a-i and 17a-i to 22a-i.
摘要翻译： 本发明提供通式5a-r，9a-1至13a-i和17a-1至22a-1的化合物，其可用作潜在的抗人癌细胞系的抗肿瘤剂。 本发明进一步提供了制备通式5a-r，9a-1至13a-i和17a-1至22a-1的吡咯并[2,1-c] [1,4]苯并二氮杂杂合物的方法。
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7.发明公开ISOXAZOLINE LINKED PYRROLO [2,1-C][1,4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND THE PROCESS FOR PREPARATTION THEREOF 有权异恶唑啉LINKED吡咯并[2,1-C] [1,4] BENZODIAZEPINHYBRIDE作为潜在抗癌剂和PROCESS FOR THEIR
公开(公告)号：EP2271648A1
公开(公告)日：2011-01-12
申请号：EP08873662.4
申请日：2008-10-31
IPC分类号： C07D487/04 , A61K31/5517 , A61P35/00
CPC分类号： C07D487/04
摘要： The present invention provides compounds of general formula (5a-d) and (9a-h) useful as potential antitumour agents against human cancer cell lines. The present invention also provides a process for the preparation of pyrrolo [2,1-
c ][1,4]benzodiazepine hybrids of general formula (5a-d) and (9a-h).
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