发明公开
- 专利标题： Neuregulin in the treatment of heart diseases
- 专利标题（中）： NRG的心脏疾病的治疗
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申请号： EP10185049.3申请日： 1999-12-21
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公开(公告)号： EP2351573A1公开(公告)日： 2011-08-03
- 发明人: Zhou, Mingdong
- 申请人： Zensun (Shanghai) Science and Technology Limited
- 申请人地址： No.68 Ju Li Road Zhangjiang Hi-Tech Park Shanghai 201203 CN
- 专利权人： Zensun (Shanghai) Science and Technology Limited
- 当前专利权人： Zensun (Shanghai) Science and Technology Limited
- 当前专利权人地址： No.68 Ju Li Road Zhangjiang Hi-Tech Park Shanghai 201203 CN
- 代理机构： Weber, Martin
- 优先权： AUPP785098 19981221
- 主分类号： A61K38/19
- IPC分类号： A61K38/19 ; A61K48/00 ; A61P9/00
摘要：
A method of causing cardiomyocyte growth and/or differentiation, the method comprising exposing a cardiomyocyte to neuregulin (NRG) thereby activating the MAP kinase pathway in the cardiomyocyte and causing growth and/or differentiation of the cardiomyocyte. Use of neuregulin, neuregulin polypeptide, neuregulin derivates, or compounds which mimic the activities of neuregulins in the treatment or management of heart disease and heart failure in a mammal.
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