发明公开
EP2361018A1 METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE
有权
方法和组合物诊断和预后肾损伤和肾功能衰竭的
- 专利标题： METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE
- 专利标题（中）： 方法和组合物诊断和预后肾损伤和肾功能衰竭的
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申请号： EP09825600.1申请日： 2009-11-10
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公开(公告)号： EP2361018A1公开(公告)日： 2011-08-31
- 发明人: ANDERBERG, Joseph , GRAY, Jeff , McPHERSON, Paul , NAKAMURA, Kevin
- 申请人： Astute Medical, Inc.
- 申请人地址： Blg 2 R. 645 3550 General Atomics Court San Diego, CA 92121 US
- 专利权人： Astute Medical, Inc.
- 当前专利权人： Astute Medical, Inc.
- 当前专利权人地址： Blg 2 R. 645 3550 General Atomics Court San Diego, CA 92121 US
- 代理机构： Schiweck, Weinzierl & Koch
- 优先权： US117180P 20081122; US117168P 20081122; US117178P 20081122; US113074P 20081110; US117163P 20081122; US115049P 20081115; US117158P 20081122; US117162P 20081122; US117160P 20081122; US117161P 20081122; US117151P 20081122
- 国际公布： WO2010054389 20100514
- 主分类号： A01N59/00
- IPC分类号： A01N59/00
摘要：
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of Clusterin, Heart-type fatty acid binding protein, Hepatocyte growth factor, Interferon gamma, Interleukin-12 subunit beta, Interleukin-16, Interleukin-2, 72 kDa type IV collagenase, Matrix metalloproteinase-9, Midkine, and Serum amyloid P-component as diagnostic and prognostic biomarkers in renal injuries.
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