发明公开
EP2370109A1 PROLIFERATION-ASSOCIATED MODULATION OF THE SPLICING OF THE INTEGRIN ALPHA 6 ISOFORMS
有权
整联ALPHA-6-异构体增殖相关调制剪接
- 专利标题： PROLIFERATION-ASSOCIATED MODULATION OF THE SPLICING OF THE INTEGRIN ALPHA 6 ISOFORMS
- 专利标题（中）： 整联ALPHA-6-异构体增殖相关调制剪接
-
申请号： EP09831355.4申请日： 2009-12-10
-
公开(公告)号： EP2370109A1公开(公告)日： 2011-10-05
- 发明人: BEAULIEU, Jean-François , HERRING, Elizabeth , BASORA, Nuria , GROULX, Jean-François
- 申请人： Socpra Sciences Santé Et Humaines S.E.C.
- 申请人地址： Suite 100 35 rue Radisson Sherbrooke, Québec J1L 1E2 CA
- 专利权人： Socpra Sciences Santé Et Humaines S.E.C.
- 当前专利权人： Socpra Sciences Santé Et Humaines S.E.C.
- 当前专利权人地址： Suite 100 35 rue Radisson Sherbrooke, Québec J1L 1E2 CA
- 代理机构： Delorme, Nicolas
- 优先权： US121337P 20081210; US177398P 20090512
- 国际公布： WO2010066046 20100617
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K31/7088 ; A61K38/17 ; A61K45/00 ; A61P35/00 ; C12Q1/68 ; G01N33/567 ; G01N33/574 ; G01N33/68 ; C12N15/63 ; C12N15/85
摘要：
This application relates to the use of agents such as expression vectors and nucleic acids encoding integrins α6 A or α6B as well as antibodies specific for those integrins which are capable of modulating the ratio between the B and A isoforms of the α6 integrin in the treatment of diseases associated with an altered proliferation rate, such as cancer. The application also relates to the use of the ratio between the B and A isoforms of the α6 integrin in the diagnosis of diseases associated with an altered proliferation rate.
公开/授权文献
信息查询
