发明公开
EP2374885A3 ENA nucleic acid drugs modifying splicing in mRNA precursor
审中-公开
在mRNA的前体ENA核酸药物的剪接的变化，
- 专利标题： ENA nucleic acid drugs modifying splicing in mRNA precursor
- 专利标题（中）： 在mRNA的前体ENA核酸药物的剪接的变化，
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申请号： EP11155685.8申请日： 2003-11-21
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公开(公告)号： EP2374885A3公开(公告)日： 2012-02-15
- 发明人: Matsuo, Masafumi , Takeshima, Yasuhiro , Koizumi, Makoto
- 申请人： Matsuo, Masafumi , Nonprofit Organization Translational Research Organization of Duchenne Muscular Dystrophy , Takeshima, Yasuhiro , KNC Laboratories Co., Ltd
- 申请人地址： Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku Kobe-shi, Hyogo 650-0017 JP
- 专利权人： Matsuo, Masafumi,Nonprofit Organization Translational Research Organization of Duchenne Muscular Dystrophy,Takeshima, Yasuhiro,KNC Laboratories Co., Ltd
- 当前专利权人： Matsuo, Masafumi,Nonprofit Organization Translational Research Organization of Duchenne Muscular Dystrophy,Takeshima, Yasuhiro,KNC Laboratories Co., Ltd
- 当前专利权人地址： Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku Kobe-shi, Hyogo 650-0017 JP
- 代理机构： Ford, Hazel
- 优先权： JP2002340857 20021125; JP2003204381 20030731
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; C07H21/04 ; A61K31/7088 ; A61K31/712 ; A61K31/7125 ; A61K48/00 ; A61P21/04
摘要：
Oligonucleotides having a nucleotide sequence complementary to nucleotide numbers such as 2571-2607, 2578-2592, 2571-2592, 2573-2592, 2578-2596, 2578-2601 or 2575-2592 of the dystrophin cDNA (Gene Bank accession No. NM_004006.1) and therapeutic agents for muscular dystrophy comprising such oligonucleotides.
公开/授权文献
- EP2374885A2 ENA nucleic acid drugs modifying splicing in mRNA precursor 公开/授权日：2011-10-12
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