发明公开
- 专利标题： INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE
- 专利标题（中）： 二酰基甘油酰基转移酶抑制剂
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申请号： EP09753000.0申请日： 2009-11-17
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公开(公告)号： EP2376454A2公开(公告)日： 2011-10-19
- 发明人: TING, Pauline C. , ASLANIAN, Robert G. , CAO, Jianhua , CAPLEN, Mary Ann , CHAN, Tin-Yau , KIM, Hyunjin , KIM, Jae-Hun , KUANG, Rongze , LEE, Joe F. , WU, Heping
- 申请人： Schering Corporation
- 申请人地址： 126 East Lincoln Avenue, RY60-30 Rahway, NJ 07065 US
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 当前专利权人地址： 126 East Lincoln Avenue, RY60-30 Rahway, NJ 07065 US
- 代理机构： Jaap, David Robert
- 优先权： US115995P 20081119
- 国际公布： WO2010059611 20100527
- 主分类号： C07D213/74
- IPC分类号： C07D213/74 ; C07D401/04 ; C07D403/14 ; C07D407/14 ; C07D409/12 ; C07D409/14 ; C07D413/12 ; C07D413/14 ; C07D417/14 ; C07D471/04 ; C07D471/10 ; C07D487/08 ; C07D493/10 ; A61K31/422 ; A61K31/427
摘要：
The present invention relates to novel heterocyclic compounds as diacylglycerol acyltransferase ("DGAT") inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose. An illustrative compound of the invention is shown below: (We bring to your attention that the illustrative compound of the invention is not provided on this electronic version as it is provided in the abstract of the paper copy)
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