发明公开
EP2391654A1 URINE AND SERUM BIOMARKERS ASSOCIATED WITH DIABETIC NEPHROPATHY
有权
随着糖尿病肾病有关的尿和SERUMBIOMARKER
- 专利标题： URINE AND SERUM BIOMARKERS ASSOCIATED WITH DIABETIC NEPHROPATHY
- 专利标题（中）： 随着糖尿病肾病有关的尿和SERUMBIOMARKER
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申请号： EP10735454.0申请日： 2010-01-27
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公开(公告)号： EP2391654A1公开(公告)日： 2011-12-07
- 发明人: LIN, Wei-Ya , YEH , Mary Ya-Ping , TSENG, Tzu-Ling , CHENG, Ping-Fu , HSU, Tsai-Wei , LI, Hung-Yi , CHEN, Yi-Ting , LIN, Yuh-Feng , CHEN, Giien-Shuen , LI , Yen-Peng
- 申请人： Industrial Technology Research Institute
- 申请人地址： No. 195, Sec. 4, Chung Hsing Road, Chutung, Hsinchu 31040 TW
- 专利权人： Industrial Technology Research Institute
- 当前专利权人： Industrial Technology Research Institute
- 当前专利权人地址： No. 195, Sec. 4, Chung Hsing Road, Chutung, Hsinchu 31040 TW
- 代理机构： Hrovat, Andrea Darinka
- 优先权： US147778P 20090128
- 国际公布： WO2010085879 20100805
- 主分类号： C07K16/38
- IPC分类号： C07K16/38 ; C07K16/18 ; C40B30/00 ; G01N33/53 ; G01N33/573 ; G01N33/68 ; C07K14/81 ; C07K14/47
摘要：
Use of urine and serum biomarkers in diagnosing diabetic nephropathy, staging diabetic nephropathy, monitoring diabetic nephropathy progress, and assessing efficacy of diabetic nephropathy treatments. These biomarkers include urine precursor alpha-2-HS-glycoprotein, urine alpha- 1 antitrypsin, urine alpha- 1 acid glycoprotein, urine osteopontin, serum osteopontin, their fragments, and combinations thereof.
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