发明公开
EP2394658A2 Passive immunization against clostridium difficile disease
审中-公开
被动免疫细菌艰难梭菌 - Erkrankung
- 专利标题: Passive immunization against clostridium difficile disease
- 专利标题(中): 被动免疫细菌艰难梭菌 - Erkrankung
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申请号: EP11002684.6申请日: 2004-12-15
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公开(公告)号: EP2394658A2公开(公告)日: 2011-12-14
- 发明人: Thomas, William D. Jr. , Giannasca, Paul J. , Zhang, Zhenxi , Lei, Wende , Monath, Thomas P.
- 申请人: Sanofi Pasteur Biologics Co.
- 申请人地址: 38 Sidney Street Cambridge, MA 02139 US
- 专利权人: Sanofi Pasteur Biologics Co.
- 当前专利权人: Sanofi Pasteur Biologics Co.
- 当前专利权人地址: 38 Sidney Street Cambridge, MA 02139 US
- 代理机构: Zwicker, Jörk
- 优先权: US737270 20031216
- 主分类号: A61K39/02
- IPC分类号: A61K39/02 ; A61K39/08 ; C07K16/12
摘要:
The invention provides active and passive immunization methods for preventing and treating Clostridium Difficile infection, which involve percutaneous administration of C. difficile toxin-neutralizing polyclonal immune globulin, C. difficile toxoids, or combinations thereof. Also provided by the invention are C. difficile toxoids, C. difficile toxin-neutralizing polyclonal immune globulin, and methods of identifying subjects that produce C. difficile toxin-neutralizing polyclonal immune globulin.
公开/授权文献
- EP2394658A3 Passive immunization against clostridium difficile disease 公开/授权日:2011-12-21
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