发明公开
EP2413701A1 SULFONYL-AZETIDIN-3-YL-METHYLAMINE AMIDE ANALOGS AS GLYT1 INHIBITORS, METHODS FOR MAKING SAME, AND USE OF SAME IN TREATING PSYCHIATRIC DISORDERS
审中-公开
磺酰基 - 氮杂环丁烷-3-基 - 甲基胺酰胺类似物ALS GlyT1抑制剂,生产和使用,用于治疗精神疾病方法
- 专利标题: SULFONYL-AZETIDIN-3-YL-METHYLAMINE AMIDE ANALOGS AS GLYT1 INHIBITORS, METHODS FOR MAKING SAME, AND USE OF SAME IN TREATING PSYCHIATRIC DISORDERS
- 专利标题(中): 磺酰基 - 氮杂环丁烷-3-基 - 甲基胺酰胺类似物ALS GlyT1抑制剂,生产和使用,用于治疗精神疾病方法
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申请号: EP10759346.9申请日: 2010-03-31
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公开(公告)号: EP2413701A1公开(公告)日: 2012-02-08
- 发明人: LINDSLEY, Craig, W. , CONN, P., Jeffrey , WILLIAMS, Richard , JONES, Carrie, K. , SHEFFLER, Douglas, J.
- 申请人: Vanderbilt University
- 申请人地址: Office Of Technology Transfer 305 Kirkland Hall Nashville, Tennessee 37240 US
- 专利权人: Vanderbilt University
- 当前专利权人: Vanderbilt University
- 当前专利权人地址: Office Of Technology Transfer 305 Kirkland Hall Nashville, Tennessee 37240 US
- 代理机构: Tostmann, Holger Carl
- 优先权: US165174P 20090331
- 国际公布: WO2010114907 20101007
- 主分类号: A01N65/00
- IPC分类号: A01N65/00
摘要:
In one aspect, the invention relates to compounds which are useful as as inhibitors of glycine type 1 transporter (GIyT1) activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with glycine type 1 transporter (GIyT1) activity using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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