发明公开
EP2413701A1 SULFONYL-AZETIDIN-3-YL-METHYLAMINE AMIDE ANALOGS AS GLYT1 INHIBITORS, METHODS FOR MAKING SAME, AND USE OF SAME IN TREATING PSYCHIATRIC DISORDERS 审中-公开
磺酰基 - 氮杂环丁烷-3-基 - 甲基胺酰胺类似物ALS GlyT1抑制剂,生产和使用,用于治疗精神疾病方法

  • 专利标题: SULFONYL-AZETIDIN-3-YL-METHYLAMINE AMIDE ANALOGS AS GLYT1 INHIBITORS, METHODS FOR MAKING SAME, AND USE OF SAME IN TREATING PSYCHIATRIC DISORDERS
  • 专利标题(中): 磺酰基 - 氮杂环丁烷-3-基 - 甲基胺酰胺类似物ALS GlyT1抑制剂,生产和使用,用于治疗精神疾病方法
  • 申请号: EP10759346.9
    申请日: 2010-03-31
  • 公开(公告)号: EP2413701A1
    公开(公告)日: 2012-02-08
  • 发明人: LINDSLEY, Craig, W.CONN, P., JeffreyWILLIAMS, RichardJONES, Carrie, K.SHEFFLER, Douglas, J.
  • 申请人: Vanderbilt University
  • 申请人地址: Office Of Technology Transfer 305 Kirkland Hall Nashville, Tennessee 37240 US
  • 专利权人: Vanderbilt University
  • 当前专利权人: Vanderbilt University
  • 当前专利权人地址: Office Of Technology Transfer 305 Kirkland Hall Nashville, Tennessee 37240 US
  • 代理机构: Tostmann, Holger Carl
  • 优先权: US165174P 20090331
  • 国际公布: WO2010114907 20101007
  • 主分类号: A01N65/00
  • IPC分类号: A01N65/00
SULFONYL-AZETIDIN-3-YL-METHYLAMINE AMIDE ANALOGS AS GLYT1 INHIBITORS, METHODS FOR MAKING SAME, AND USE OF SAME IN TREATING PSYCHIATRIC DISORDERS
摘要:
In one aspect, the invention relates to compounds which are useful as as inhibitors of glycine type 1 transporter (GIyT1) activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with glycine type 1 transporter (GIyT1) activity using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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