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1.发明公开
公开(公告)号：EP2381941A1
公开(公告)日：2011-11-02
申请号：EP09837121.4
申请日：2009-12-29
发明人： LINDSLEY, Craig, W. , CONN, P., Jeffrey , WEAVER, Charles, David , NISWENDER, Colleen, M. , WILLIAMS, Richard , JONES, Carrie, K. , SHEFFLER, Douglas, J.
IPC分类号： A61K31/397 , A61K31/407
CPC分类号： C07D209/52 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12
摘要： In one aspect, the invention relates to compounds which are useful as as inhibitors of glycine type 1 transporter (GIyTl) activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with glycine type 1 transporter (GIyTl) activity using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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2.发明公开SULFONYL-AZETIDIN-3-YL-METHYLAMINE AMIDE ANALOGS AS GLYT1 INHIBITORS, METHODS FOR MAKING SAME, AND USE OF SAME IN TREATING PSYCHIATRIC DISORDERS 审中-公开磺酰基 - 氮杂环丁烷-3-基 - 甲基胺酰胺类似物ALS GlyT1抑制剂，生产和使用，用于治疗精神疾病方法
公开(公告)号：EP2413701A1
公开(公告)日：2012-02-08
申请号：EP10759346.9
申请日：2010-03-31
发明人： LINDSLEY, Craig, W. , CONN, P., Jeffrey , WILLIAMS, Richard , JONES, Carrie, K. , SHEFFLER, Douglas, J.
IPC分类号： A01N65/00
CPC分类号： C07D401/14 , C07D205/04 , C07D403/12 , C07D409/14
摘要： In one aspect, the invention relates to compounds which are useful as as inhibitors of glycine type 1 transporter (GIyT1) activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with glycine type 1 transporter (GIyT1) activity using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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3.发明公开ALKYLSULFONYL-2,3-DIHYDROSPIRO[INDENE-1,4'-PIPERIDINE] ANALOGS AS GLYT1 INHIBITORS, METHODS FOR MAKING SAME, AND USE OF SAME IN TREATING PSYCHIATRIC DISORDERS 审中-公开作为GLYT1抑制剂的烷基磺酰基-2,3-二氢吡咯[茚-1,4'-哌啶]类似物，其制备方法及其在治疗精神障碍中的应用
公开(公告)号：EP2403337A2
公开(公告)日：2012-01-11
申请号：EP10749264.7
申请日：2010-03-03
发明人： LINDSLEY, Craig, W. , CONN, Jeffrey, P. , WILLIAMS, Richard , JONES, Carrie, K. , SHEFFLER, Douglas, J.
IPC分类号： A01N43/42
CPC分类号： C07D221/20 , C07D401/12 , C07D409/12
摘要： In one aspect, the invention relates to compounds which are useful as as inhibitors of glycine type 1 transporter (GIyT1) activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with glycine type 1 transporter (GIyT1) activity using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译： 一方面，本发明涉及用作甘氨酸1型转运蛋白（GlyT1）活性抑制剂的化合物; 用于制备该化合物的合成方法; 包含该化合物的药物组合物 和使用该化合物和组合物治疗与甘氨酸1型转运蛋白（GlyT1）活性有关的疾病的方法。 该摘要旨在作为用于在特定领域中进行搜索的目的的扫描工具，并且不旨在限制本发明。
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4.发明公开
公开(公告)号：EP2378885A1
公开(公告)日：2011-10-26
申请号：EP09832601.0
申请日：2009-12-11
发明人： LINDSLEY, Craig, W. , CONN, P., Jeffrey , WEAVER, Charles, David , NISWENDER, Colleen, M. , WILLIAMS, Richard , JONES, Carrie, K. , SHEFFLER, Douglas, J.
IPC分类号： A01N55/02
CPC分类号： C07D209/52 , C07D403/12
摘要： In one aspect, the invention relates to compounds which are useful as inhibitors of glycine type 1 transporter (GIyT1) activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with glycine type 1 transporter (GIyT1) activity using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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搜索结果
4 条记录 (耗时 0.016 秒)
