发明公开
- 专利标题: LIPID COMPOSITIONS
- 专利标题(中): 脂肪组成
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申请号: EP10772790.1申请日: 2010-05-05
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公开(公告)号: EP2416760A1公开(公告)日: 2012-02-15
- 发明人: MANOHARAN, Muthiah , RAJEEV, Kallanthottathil, G. , JAYARAMAN, Muthusamy , BUTLER, David , JUNG, Michael, E.
- 申请人: Alnylam Pharmaceuticals, Inc. , Manoharan, Muthiah , Rajeev, Kallanthottathil G. , Jayaraman, Muthusamy , Butler, David , Jung, Michael, E.
- 申请人地址: 300 Third Street Cambridge, MA 02142 US
- 专利权人: Alnylam Pharmaceuticals, Inc.,Manoharan, Muthiah,Rajeev, Kallanthottathil G.,Jayaraman, Muthusamy,Butler, David,Jung, Michael, E.
- 当前专利权人: Alnylam Pharmaceuticals, Inc.,Manoharan, Muthiah,Rajeev, Kallanthottathil G.,Jayaraman, Muthusamy,Butler, David,Jung, Michael, E.
- 当前专利权人地址: 300 Third Street Cambridge, MA 02142 US
- 代理机构: Müller-Boré & Partner Patentanwälte
- 优先权: US175770P 20090505; US299291P 20100128
- 国际公布: WO2010129709 20101111
- 主分类号: A61K9/127
- IPC分类号: A61K9/127 ; A61K31/50
摘要:
Disclosed herein are lipid compositions comprising a cationic lipid formula (I), a neutral lipid, a sterol and a PEG or PEG-modified lipid, wherein formula (I) is (F). Also disclosed are methods of producing the cationic lipid of formula (I).
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