发明授权
- 专利标题： PYRIMIDINE INHIBITORS OF KINASE ACTIVITY
- 专利标题（中）： 硫嘌呤活性抑制剂
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申请号： EP10727227.0申请日： 2010-05-26
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公开(公告)号： EP2435435B1公开(公告)日： 2014-01-29
- 发明人: CLARK, Richard, F. , BA-MAUNG, Nwe, Y. , ERICKSON, Scott, A. , FIDANZE, Steve, D. , MANTEI, Robert, A. , SHEPPARD, George, S. , SORENSEN, Bryan, K. , WANG, Gary, T. , WANG, Jieyi , BELL, Randy, L.
- 申请人： AbbVie Inc.
- 申请人地址： 1 North Waukegan Road North Chicago, IL 60064 US
- 专利权人： AbbVie Inc.
- 当前专利权人： AbbVie Inc.
- 当前专利权人地址： 1 North Waukegan Road North Chicago, IL 60064 US
- 代理机构： Modiano, Micaela Nadia
- 优先权： US181555P 20090527
- 国际公布： WO2010138575 20101202
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D487/04 ; C07D513/04 ; C07D403/14 ; A61K31/506 ; A61P35/00
摘要：
Described herein are compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, L1, R2, R3, n, p, Ar1, and Ar2 are defined in the description. Methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-1R are also disclosed.
公开/授权文献
- EP2435435A1 PYRIMIDINE INHIBITORS OF KINASE ACTIVITY 公开/授权日：2012-04-04
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