发明公开
- 专利标题： PYRIMIDINE INHIBITORS OF KINASE ACTIVITY
- 专利标题（中）： 硫嘌呤活性抑制剂
-
申请号： EP10727227.0申请日： 2010-05-26
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公开(公告)号： EP2435435A1公开(公告)日： 2012-04-04
- 发明人: CLARK, Richard, F. , BA-MAUNG, Nwe, Y. , ERICKSON, Scott, A. , FIDANZE, Steve, D. , MANTEI, Robert, A. , SHEPPARD, George, S. , SORENSEN, Bryan, K. , WANG, Gary, T. , WANG, Jieyi , BELL, Randy, L.
- 申请人： Abbott Laboratories
- 申请人地址： Department D377/AP6A-1 100 Abbott Park Road Abbott Park, Illinois 60064-6008 US
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： Department D377/AP6A-1 100 Abbott Park Road Abbott Park, Illinois 60064-6008 US
- 代理机构： Modiano, Micaela Nadia
- 优先权： US181555P 20090527
- 国际公布： WO2010138575 20101202
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D487/04 ; C07D513/04 ; C07D403/14 ; A61K31/506 ; A61P35/00
摘要：
Described herein are compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G
1 , L
1 , R
2 , R
3 , n, p, Ar
1 , and Ar
2 are defined in the description. Methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-IR are also disclosed.
1 , L
1 , R
2 , R
3 , n, p, Ar
1 , and Ar
2 are defined in the description. Methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-IR are also disclosed.
公开/授权文献
- EP2435435B1 PYRIMIDINE INHIBITORS OF KINASE ACTIVITY 公开/授权日：2014-01-29
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