发明公开
- 专利标题： FUSED TRICYCLIC COMPOUNDS AS NOVEL mTOR INHIBITORS
- 专利标题（中）： 稠合三环化合物作为mTOR抑制剂
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申请号： EP10730016.2申请日： 2010-06-30
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公开(公告)号： EP2448942A1公开(公告)日： 2012-05-09
- 发明人: CHENG, Cliff, C. , ZENG, Hongbo , SHIPPS, Jr., Gerald, W. , DENG, Yongqi , MENG, Zhaoyang , ZHAO, Lianyun , NAN, Yang , SUN, Binyuan , LIU, Duan , REDDY, Panduranga, A. , SIDDIQUI, M., Arshad
- 申请人： Schering Corporation
- 申请人地址： 2000 Galloping Hill Road Kenilworth, NJ 07033 US
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 当前专利权人地址： 2000 Galloping Hill Road Kenilworth, NJ 07033 US
- 代理机构： Hussain, Deeba
- 优先权： US222529P 20090702
- 国际公布： WO2011002887 20110106
- 主分类号： C07D487/14
- IPC分类号： C07D487/14 ; A61K31/519 ; A61P35/00
摘要：
The present invention provides Fused Tricyclic Compounds of the Formula (I) wherein Q, R
1 , R
2 , R
3 , and R
4 are as defined herein, and pharmaceutically acceptable salts of such Fused Tricyclic Compounds. The Fused Tricyclic Compounds are useful in the treatment of cancer and other proliferative disorders.
1 , R
2 , R
3 , and R
4 are as defined herein, and pharmaceutically acceptable salts of such Fused Tricyclic Compounds. The Fused Tricyclic Compounds are useful in the treatment of cancer and other proliferative disorders.
公开/授权文献
- EP2448942B1 FUSED TRICYCLIC COMPOUNDS AS mTOR INHIBITORS 公开/授权日：2014-09-24
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