发明公开
EP2473157A1 KETOROLAC TROMETHAMINE COMPOSITIONS FOR TREATING OR PREVENTING OCULAR PAIN
有权
KETOROLAC-TROMETHAMIN-ZUSAMMENSETZUNGEN ZUR BEHANDLUNG ODER PRENVENTION VON SCHMERZ
- 专利标题： KETOROLAC TROMETHAMINE COMPOSITIONS FOR TREATING OR PREVENTING OCULAR PAIN
- 专利标题（中）： KETOROLAC-TROMETHAMIN-ZUSAMMENSETZUNGEN ZUR BEHANDLUNG ODER PRENVENTION VON SCHMERZ
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申请号： EP10754617.8申请日： 2010-08-31
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公开(公告)号： EP2473157A1公开(公告)日： 2012-07-11
- 发明人: FARNES, Eldon Quinn , ATTAR, Mayssa , SCHIFFMAN, Rhett M. , CHANG, Chin-Ming , GRAHAM, Richard S. , WELTY, Devin
- 申请人： Allergan, Inc.
- 申请人地址： 2525 Dupont Drive Irvine, CA 92612 US
- 专利权人： Allergan, Inc.
- 当前专利权人： Allergan, Inc.
- 当前专利权人地址： 2525 Dupont Drive Irvine, CA 92612 US
- 代理机构： HOFFMANN EITLE
- 优先权： US552057 20090901
- 国际公布： WO2011028718 20110310
- 主分类号： A61K9/00
- IPC分类号： A61K9/00 ; A61K47/38 ; A61K31/407
摘要：
The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution which provides increased visual acuity in users and wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient which is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac.
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