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1.发明公开KETOROLAC TROMETHAMINE COMPOSITIONS FOR TREATING OR PREVENTING OCULAR PAIN 有权KETOROLAC-TROMETHAMIN-ZUSAMMENSETZUNGEN ZUR BEHANDLUNG ODER PRENVENTION VON SCHMERZ
公开(公告)号：EP2473157A1
公开(公告)日：2012-07-11
申请号：EP10754617.8
申请日：2010-08-31
申请人： Allergan, Inc.
发明人： FARNES, Eldon Quinn , ATTAR, Mayssa , SCHIFFMAN, Rhett M. , CHANG, Chin-Ming , GRAHAM, Richard S. , WELTY, Devin
IPC分类号： A61K9/00 , A61K47/38 , A61K31/407
CPC分类号： A61K31/407 , A61K9/0048 , A61K9/08 , A61K31/14 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/186 , A61K47/38
摘要： The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution which provides increased visual acuity in users and wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient which is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac.
摘要翻译： 本发明提供了在水溶液中具有有效量的酮咯酸和羧甲基纤维素的水性眼用溶液，其提供增加的视敏度，并且其中选择羧甲基纤维素的浓度以提供在患者的眼睛中增加酮咯酸的吸收， 比具有相同浓度的酮咯酸的对比水性酮咯酸眼药液的吸收大至少130％。
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2.发明授权
公开(公告)号：EP2473157B1
公开(公告)日：2017-11-15
申请号：EP10754617.8
申请日：2010-08-31
申请人： ALLERGAN, INC.
发明人： FARNES, Eldon Quinn , ATTAR, Mayssa , SCHIFFMAN, Rhett M. , CHANG, Chin-Ming , GRAHAM, Richard S. , WELTY, Devin
IPC分类号： A61K9/00 , A61K47/38 , A61K31/407
CPC分类号： A61K31/407 , A61K9/0048 , A61K9/08 , A61K31/14 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/186 , A61K47/38
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3.发明授权
公开(公告)号：EP2257275B1
公开(公告)日：2011-12-28
申请号：EP09716497.4
申请日：2009-03-03
申请人： Allergan, Inc.
发明人： FARNES, Eldon Quinn , ATTAR, Mayssa , SCHIFFMAN, Rhett M. , CHANG, Chin-ming , GRAHAM, Richard S. , WELTY, Devin F.
CPC分类号： A61K31/14 , A61K9/0048 , A61K31/407 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/186 , A61K47/38
摘要： The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient that is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac.
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4.发明公开
公开(公告)号：EP2257275A2
公开(公告)日：2010-12-08
申请号：EP09716497.4
申请日：2009-03-03
申请人： Allergan, Inc.
发明人： FARNES, Eldon Quinn , ATTAR, Mayssa , SCHIFFMAN, Rhett M. , CHANG, Chin-ming , GRAHAM, Richard S. , WELTY, Devin F.
CPC分类号： A61K31/14 , A61K9/0048 , A61K31/407 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/186 , A61K47/38
摘要： The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient that is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac.
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