发明授权
- 专利标题: Adenoviral vector encoding malaria antigen
- 专利标题(中): 编码疟疾抗原的腺病毒载体
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申请号: EP12164331.6申请日: 2008-04-10
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公开(公告)号: EP2486939B1公开(公告)日: 2017-07-12
- 发明人: Reyes, Arturo , Hill, Adrian , O'Hara, Geraldine , Colloca, Stefano , Cortese, Riccardo
- 申请人: Oxford University Innovation Limited , GlaxoSmithKline Biologicals SA
- 申请人地址: Buxton Court 3 West Way Botley Oxford OX2 0JB GB
- 专利权人: Oxford University Innovation Limited,GlaxoSmithKline Biologicals SA
- 当前专利权人: Oxford University Innovation Limited,GlaxoSmithKline Biologicals SA
- 当前专利权人地址: Buxton Court 3 West Way Botley Oxford OX2 0JB GB
- 代理机构: Dalton, Marcus Jonathan William
- 优先权: GB0706914 20070410; GB0717888 20070913
- 主分类号: C12N15/86
- IPC分类号: C12N15/86 ; C07K14/445 ; C07K16/20 ; C07K14/78 ; A61K39/015
摘要:
The invention provides recombinant adenoviral vectors which are capable of eliciting immunity against the pre-erythrocytic stage of the life cycle of the malaria parasite. In particular, the invention provides a recombinant, replication deficient simian adenoviral vector which encodes an antigen comprising the thrombospondin-related adhesion protein (TRAP), and also immunogenic compositions (e.g. vaccines) comprising the vector and methods of using such compositions.
公开/授权文献
- EP2486939A1 Adenoviral vector encoding malaria antigen 公开/授权日:2012-08-15
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