发明公开
- 专利标题: TRANSDERMALLY ABSORBABLE DONEPEZIL-CONTAINING PREPARATION
- 专利标题(中): 经皮吸收DONEPEZILHALTIGE研制
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申请号: EP10824887.3申请日: 2010-10-18
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公开(公告)号: EP2491931A1公开(公告)日: 2012-08-29
- 发明人: KAWAKAMI, Satoshi , YAMAJI, Masahiro
- 申请人: Teikoku Seiyaku Co., Ltd.
- 申请人地址: 567 Sanbonmatsu Higashikagawa-shi, Kagawa 769-2695 JP
- 专利权人: Teikoku Seiyaku Co., Ltd.
- 当前专利权人: Teikoku Seiyaku Co., Ltd.
- 当前专利权人地址: 567 Sanbonmatsu Higashikagawa-shi, Kagawa 769-2695 JP
- 代理机构: Albrecht, Thomas
- 优先权: JP2009242656 20091021
- 国际公布: WO2011049038 20110428
- 主分类号: A61K31/445
- IPC分类号: A61K31/445 ; A61K9/08 ; A61K9/70 ; A61K47/10 ; A61K47/14 ; A61K47/22 ; A61K47/34 ; A61P25/28
摘要:
Provided is a donepezil-containing transdermal absorption formulation that can sustainably administer donepezil for a long period of time, and can provide both a rapid increase in the blood level of donepezil and donepezil sustained release properties. The donepezil-containing transdermal absorption formulation is a transdermal absorption formulation produced by dissolving donepezil, which is the active ingredient, in an adhesive patch base that contains a hydrophobic polymer and an absorption promoter. The absorption promoter is one kind or two or more kinds selected from lauryl alcohol, triethyl citrate, isopropyl myristate, cetyl lactate, oleyl alcohol, sorbitan monooleate, polyethylene glycol monostearate, lauromacrogol, N-methyl-2-pyrrolidone, and triacetin.
公开/授权文献
- EP2491931B1 TRANSDERMALLY ABSORBABLE DONEPEZIL-CONTAINING PREPARATION 公开/授权日:2017-09-20
信息查询
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