发明公开
EP2496942A1 METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE
有权
方法和组合物诊断和预后肾损伤和肾功能衰竭的
- 专利标题： METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE
- 专利标题（中）： 方法和组合物诊断和预后肾损伤和肾功能衰竭的
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申请号： EP10829198.0申请日： 2010-11-05
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公开(公告)号： EP2496942A1公开(公告)日： 2012-09-12
- 发明人: ANDERBERG, Joseph , GRAY, Jeff , MCPHERSON, Paul , NAKAMURA, Kevin , KAMPF, James, Patrick
- 申请人： Astute Medical, Inc.
- 申请人地址： Blg 2 R. 645 3550 General Atomics Court San Diego, CA 92121 US
- 专利权人： Astute Medical, Inc.
- 当前专利权人： Astute Medical, Inc.
- 当前专利权人地址： Blg 2 R. 645 3550 General Atomics Court San Diego, CA 92121 US
- 代理机构： Schiweck, Weinzierl & Koch
- 优先权： US259540P 20091109; US259142P 20091107; US259140P 20091107; US259141P 20091107; US259511P 20091109; US259163P 20091107; US259143P 20091107
- 国际公布： WO2011057147 20110512
- 主分类号： G01N33/53
- IPC分类号： G01N33/53
摘要：
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of Cathepsin B, Renin, Dipeptidyl Peptidase IV, Neprilysin, Beta-2-microglobulin, Carbonic anhydrase IX, and C-X-C motif chemokine 2 as diagnostic and prognostic biomarkers in renal injuries.
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