发明公开
EP2545939A2 Methods of administering tetrahydrobiopterin, associated compositions, and methods of measuring
审中-公开
施用四氢生物蝶呤的方法，相关组合物和测量方法
- 专利标题： Methods of administering tetrahydrobiopterin, associated compositions, and methods of measuring
- 专利标题（中）： 施用四氢生物蝶呤的方法，相关组合物和测量方法
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申请号： EP12005352.5申请日： 2008-04-11
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公开(公告)号： EP2545939A2公开(公告)日： 2013-01-16
- 发明人: Oppenheimer, Daniel I. , Dorenbaum, Alejandro , Okhamafe, Augustus , Foehr, Erik , Castillo, Sianna , Kostel, Paul John
- 申请人： BioMarin Pharmaceutical Inc.
- 申请人地址： 105 Digital Drive Novato, CA 94949 US
- 专利权人： BioMarin Pharmaceutical Inc.
- 当前专利权人： BioMarin Pharmaceutical Inc.
- 当前专利权人地址： 105 Digital Drive Novato, CA 94949 US
- 代理机构： Benz, Jürgen
- 主分类号： A61K45/06
- IPC分类号： A61K45/06 ; A61K9/20 ; A61K9/48 ; A61K31/519 ; A61P3/00 ; A61P3/02 ; A61P25/16 ; A61K9/00
摘要：
The present invention is directed to treatment methods of administering tetrahydrobiopterin, including in oral dosage forms, in intravenous formulations, and with food. Also disclosed herein are biopterin assays for measuring the amount of biopterin and metabolites of biopterin in a sample.
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