发明公开
EP2550254A1 CYCLOPENTYL - AND CYCLOHEPTYLPYRAZOLES AS FXR MODULATORS
审中-公开
环戊二烯并吡咯并吡唑(FXR-MODULATOREN)
- 专利标题: CYCLOPENTYL - AND CYCLOHEPTYLPYRAZOLES AS FXR MODULATORS
- 专利标题(中): 环戊二烯并吡咯并吡唑(FXR-MODULATOREN)
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申请号: EP11711495.9申请日: 2011-03-21
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公开(公告)号: EP2550254A1公开(公告)日: 2013-01-30
- 发明人: BENSON, Gregory Martin , BLEICHER, Konrad , GRETHER, Uwe , KUHN, Bernd , RICHTER, Hans , TAYLOR, Sven
- 申请人: F.Hoffmann-La Roche AG
- 申请人地址: Grenzacherstrasse 124 4070 Basel CH
- 专利权人: F.Hoffmann-La Roche AG
- 当前专利权人: F.Hoffmann-La Roche AG
- 当前专利权人地址: Grenzacherstrasse 124 4070 Basel CH
- 代理机构: Salud, Carlos E.
- 优先权: EP10157484 20100324
- 国际公布: WO2011117163 20110929
- 主分类号: C07D231/54
- IPC分类号: C07D231/54 ; C07D401/12 ; C07D403/12 ; A61K31/416 ; A61K31/4439 ; A61P3/04 ; A61P3/06 ; A61P3/10 ; A61P25/16 ; A61P25/28 ; A61P35/00
摘要:
This invention relates to novel cyclopentyl- and cycloheptylpyrazole derivatives of the formula (I) wherein A and R
1 to R
4 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof, to compositions including these compounds and methods of using the compounds.
1 to R
4 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof, to compositions including these compounds and methods of using the compounds.
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