发明公开
EP2550258A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
有权
细胞凋亡诱导剂治疗癌症和免疫及自身免疫疾病
- 专利标题: APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
- 专利标题(中): 细胞凋亡诱导剂治疗癌症和免疫及自身免疫疾病
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申请号: EP11709579.4申请日: 2011-03-10
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公开(公告)号: EP2550258A2公开(公告)日: 2013-01-30
- 发明人: DING, Hong , ELMORE, Steven , HEXAMER, Laura , KUNZER, Aaron, R. , PARK, Cheol-Min , SOUERS, Andrew, J. , SULLIVAN, Gerard , WENDT, Michael
- 申请人: Abbvie Inc.
- 申请人地址: 1 North Waukegan Road North Chicago, IL 60064 US
- 专利权人: Abbvie Inc.
- 当前专利权人: Abbvie Inc.
- 当前专利权人地址: 1 North Waukegan Road North Chicago, IL 60064 US
- 代理机构: Modiano, Micaela Nadia
- 优先权: US317575P 20100325
- 国际公布: WO2011119345 20110929
- 主分类号: C07D295/112
- IPC分类号: C07D295/112 ; C07D295/195 ; C07D417/04 ; C07D211/58 ; C07C311/51 ; A61K31/451 ; A61K31/495 ; A61K31/18 ; A61P35/00
摘要:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti apoptotic Bcl-2 protein.
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