发明公开
EP2552209A1 NOVEL SPIRO IMIDAZOLONE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE
审中-公开
NEW SPIROIMIDAZOLON衍生物作为胰高血糖素受体拮抗剂，THEREOF组合物及其使用方法
- 专利标题： NOVEL SPIRO IMIDAZOLONE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE
- 专利标题（中）： NEW SPIROIMIDAZOLON衍生物作为胰高血糖素受体拮抗剂，THEREOF组合物及其使用方法
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申请号： EP11760027.0申请日： 2011-03-22
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公开(公告)号： EP2552209A1公开(公告)日： 2013-02-06
- 发明人: DEMONG, Duane, E. , MILLER, Michael, W. , DAI, Xing , WONG, Michael, K. , LAVEY, Brian, J. , YU, Wensheng , ZHOU, Guowei , STAMFORD, Andrew, W. , KOZLOWSKI, Joseph, A. , GREENLEE, William, J.
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 代理机构： Jaap, David Robert
- 优先权： US317771P 20100326
- 国际公布： WO2011119541 20110929
- 主分类号： A01N43/52
- IPC分类号： A01N43/52
摘要：
The present invention relates to compounds of the general formula (I): wherein ring A, ring B, G, R3, Z, L1, and L2 are selected independently of each other and are as defined herein, to compositions comprising the compounds, and to methods of using the compounds as glucagon receptor antagonists and for the treatment or prevention of type 2 diabetes and conditions related thereto.
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