发明公开
- 专利标题： NOVEL PEPTIDES AND METHODS FOR THEIR PREPARATION AND USE
- 专利标题（中）： 新的肽和生产它们的用途方法
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申请号： EP11711424.9申请日： 2011-03-23
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公开(公告)号： EP2552471A1公开(公告)日： 2013-02-06
- 发明人: ALSINA-FERNANDEZ, Jorge , BOKVIST, Krister Bengt , GUO, Lili , MAYER, John Philip
- 申请人： ELI LILLY AND COMPANY
- 申请人地址： Lilly Corporate Center Indianapolis, IN 46285 US
- 专利权人： ELI LILLY AND COMPANY
- 当前专利权人： ELI LILLY AND COMPANY
- 当前专利权人地址： Lilly Corporate Center Indianapolis, IN 46285 US
- 代理机构： Kent, Lindsey Ruth
- 优先权： US317850P 20100326
- 国际公布： WO2011119657 20110929
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; C07K14/47 ; C07K14/62 ; A61K38/30 ; A61K38/26 ; C07K14/605
摘要：
The present invention is in the field of treatment of diabetes and relates to peptides that exhibit activity for both glucose-dependent insulinotropic peptide receptor (GIP-R) and glucagon-like peptide- 1 receptor (GLP-1-R) and are selective over glucagon receptor (Gluc-R). Specifically provided are GIP analogs with amino acid substitutions introduced to modulate activity for both GIP-R and GLP-1-R and maintain selectivity over Gluc-R.
公开/授权文献
- EP2552471B1 NOVEL PEPTIDES AND METHODS FOR THEIR PREPARATION AND USE 公开/授权日：2016-03-16
信息查询
IPC分类:
