发明公开
- 专利标题： NOVEL DNA-BINDING PROTEINS AND USES THEREOF
- 专利标题（中）： NEER DNA-BINDENDE蛋白在VERWENDUNGEN DAVON
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申请号： EP11783865.6申请日： 2011-05-17
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公开(公告)号： EP2571512A1公开(公告)日： 2013-03-27
- 发明人: GREGORY, Philip, D. , MILLER, Jeffrey, C. , PASCHON, David , REBAR, Edward, J. , TAN, Siyuan , URNOV, Fyodor , ZHANG, Lei
- 申请人： Sangamo BioSciences, Inc.
- 申请人地址： Point Richmond Tech. Center 501 Canal Boulevard Suite A100 Richmond, CA 94804 US
- 专利权人： Sangamo BioSciences, Inc.
- 当前专利权人： Sangamo BioSciences, Inc.
- 当前专利权人地址： Point Richmond Tech. Center 501 Canal Boulevard Suite A100 Richmond, CA 94804 US
- 代理机构： Weiss, Wolfgang
- 优先权： US201161465869P 20110324; US201161462482P 20110202; US201061459891P 20101220; US455121P 20101013; US401429P 20100812; US395836P 20100517
- 国际公布： WO2011146121 20111124
- 主分类号： A61K38/16
- IPC分类号： A61K38/16
摘要：
Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.
公开/授权文献
- EP2571512B1 NOVEL DNA-BINDING PROTEINS AND USES THEREOF 公开/授权日：2017-08-23
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