- 专利标题： AROMATIC BUTAN-2-OL COMPOUNDS, PREPARATION METHODS AND USES THEREOF
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申请号： EP11782849.1申请日： 2011-05-16
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公开(公告)号： EP2573067B1公开(公告)日： 2018-10-10
- 发明人: LI, Song , ZHONG, Wu , LIU, Ping , XIAO, Junhai , ZHENG, Zhibing , XIE, Yunde , ZHAO, Guoming , WANG, Xiaokui , WANG, Lili , LI, Xingzhou , ZHOU, Xinbo
- 申请人： Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
- 申请人地址： No. 27, Taiping Road Haidian District Beijing 100-850 CN
- 专利权人： Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
- 当前专利权人： Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
- 当前专利权人地址： No. 27, Taiping Road Haidian District Beijing 100-850 CN
- 代理机构： Weickmann & Weickmann PartmbB
- 优先权： CN201010173785 20100517
- 国际公布： WO2011143932 20111124
- 主分类号： C07C215/62
- IPC分类号： C07C215/62 ; C07C217/72 ; A61K31/137 ; A61P31/06
摘要：
The present invention relates to aromatic butan-2-ol compounds and preparation methods and uses thereof. Specifically, the present invention relates to the compound of Formula I, or an optical isomer, racemate, diastereomer, pharmaceutically acceptable salt or solvate thereof: wherein each of the substituents have the definitions as given in the specification. The present invention further relates to a pharmaceutical composition containing the compound, and the use of the compound in manufacture of a medicament for the treatment and/or prophylaxis of a disease or disorder caused by tubercle bacillus infection. The compound of Formula I of the present invention has advantages in treatment and/or prophylaxis of a disease or disorder caused by tubercle bacillus infection.
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