发明公开
EP2580344A1 FLUORESCENT -LABELLED DIUBIQUITIN SUBSTRATE FOR A DEUBIQUITINASE ASSAY 有权
荧光标记的二硫苏糖酸底物用于DEUBIQUITIITINASE测定

  • 专利标题: FLUORESCENT -LABELLED DIUBIQUITIN SUBSTRATE FOR A DEUBIQUITINASE ASSAY
  • 专利标题(中): 荧光标记的二硫苏糖酸底物用于DEUBIQUITIITINASE测定
  • 申请号: EP11729135.1
    申请日: 2011-06-14
  • 公开(公告)号: EP2580344A1
    公开(公告)日: 2013-04-17
  • 发明人: KOMANDER, DavidYE, Yu
  • 申请人: Medical Research Council
  • 申请人地址: 7th Floor Lynton House 7-12 Tavistock Square London WC1H 9LT GB
  • 专利权人: Medical Research Council
  • 当前专利权人: Medical Research Council
  • 当前专利权人地址: 7th Floor Lynton House 7-12 Tavistock Square London WC1H 9LT GB
  • 代理机构: Maschio, Antonio
  • 优先权: GB201009941 20100614
  • 国际公布: WO2011157982 20111222
  • 主分类号: C12Q1/37
  • IPC分类号: C12Q1/37
FLUORESCENT -LABELLED DIUBIQUITIN SUBSTRATE FOR A DEUBIQUITINASE ASSAY
摘要:
There is described a substrate for measuring the activity of a deubiquitinating enzyme (DUB), comprising a diubiquitin molecule, wherein an ubiquitin monomer is labeled with a fluorescent label, as well as an assay for DUB enzymes using such substrates.
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