Machine for spreading out and loading flat articles of clothing (A) comprising a conveyor belt (30) and loading clamps (24a, 24b) which receive contiguous corners (A1, A2) of a flat article of clothing (A) manually loaded by an operator (P) in a loading station (1) and transfer them to spreading clamps (4a, 4b), whereby each of said loading clamps (24a, 24b) has a loading jaw (51) driven by an actuator (52) and an auxiliary loading jaw (53) with yielding and recovery capacity for catching parts of the corners (A1, A2) against opposite sides of said loading support (50), and an air blowing nozzle (55) producing an airflow capable of pushing a portion of said corners (A1, A2) released from the auxiliary loading jaw (53) and introducing said portion of sad corners (A1, A2) between the jaws of a corresponding spreading clamp (4a, 4b) driven by an actuator (58) for catching the portions of th corners (A1, A2) previously released.