发明公开
EP2595953A1 PROCEDE DE SYNTHESE D'ISOTHIOCYANATES ET LEURS DERIVES ET UTILISATIONS DE CEUX-CI
审中-公开
过程衍生品和异硫氰酸酯，以及它们的用途的合成
- 专利标题： PROCEDE DE SYNTHESE D'ISOTHIOCYANATES ET LEURS DERIVES ET UTILISATIONS DE CEUX-CI
- 专利标题（英）： Process for the synthesis of isothiocyanates and derivatives thereof and uses of same
- 专利标题（中）： 过程衍生品和异硫氰酸酯，以及它们的用途的合成
-
申请号： EP11734106.5申请日： 2011-07-20
-
公开(公告)号： EP2595953A1公开(公告)日： 2013-05-29
- 发明人: DUBOIS, Jacques , MARCHAL, Alfred , LACROIX, Damien , CABOU, Jérôme
- 申请人： Auriga International
- 申请人地址： Chemin des Rousettes 2 1410 Waterloo BE
- 专利权人： Auriga International
- 当前专利权人： Auriga International
- 当前专利权人地址： Chemin des Rousettes 2 1410 Waterloo BE
- 代理机构： Coulon, Ludivine
- 优先权： BE201000456 20100723
- 国际公布： WO2012010644 20120126
- 主分类号： C07C315/02
- IPC分类号： C07C315/02 ; C07C317/28 ; C07C319/14 ; C07C319/20 ; C07C323/25 ; C07C323/60 ; C07C331/20 ; C07C333/04 ; C07C333/20 ; C07C335/08 ; C07D211/06 ; C07D241/04 ; C07D265/30 ; A61K31/17 ; A61K31/26
摘要：
Process for the synthesis of an isothiocyanate of general formula (I) SCN‑R
1 -R
4 -R
2 in which R
1 and R
2 represent, independently of one another, an alkyl, aryl or alkylaryl group, R
4 represents a carbonyl, sulphinyl or sulphonyl group or a sulphide and derivatives thereof comprising a step of reacting an alkylalkylamine having the general formula (II) NH
2
_ R
1
_ R
4
_ R
2 in which R
1 and R
2 represent, independently of one another, an alkyl, aryl or alkylaryl group, R
4 represents a carbonyl, sulphinyl, sulphonyl or sulphide group, in the presence of carbon sulphide and of di-
tert -butyl dicarbonate with formation of the aforesaid corresponding isothiocyanate, compounds obtained by this process and also uses thereof.
1 -R
4 -R
2 in which R
1 and R
2 represent, independently of one another, an alkyl, aryl or alkylaryl group, R
4 represents a carbonyl, sulphinyl or sulphonyl group or a sulphide and derivatives thereof comprising a step of reacting an alkylalkylamine having the general formula (II) NH
2
_ R
1
_ R
4
_ R
2 in which R
1 and R
2 represent, independently of one another, an alkyl, aryl or alkylaryl group, R
4 represents a carbonyl, sulphinyl, sulphonyl or sulphide group, in the presence of carbon sulphide and of di-
tert -butyl dicarbonate with formation of the aforesaid corresponding isothiocyanate, compounds obtained by this process and also uses thereof.
信息查询
