发明公开
EP2617434A1 HIV-1 integrase deficient immunogens and methods for loading dendritic cells with said immunogens 审中-公开
HIV-1-Integrase-defiziente Immunogene und Verfahren zum Beladen von dentritischen Zellen mit besagten Immunogenen

HIV-1 integrase deficient immunogens and methods for loading dendritic cells with said immunogens
摘要:
The present invention relates to a method for obtaining an antigen-loaded dendritic cell in vitro comprising contacting an immature dendritic cell with an immunogen, preferably a HIV immunogen, and simultaneously, during at least part of said step, placing said immature dendritic cell under conditions adequate for maturation. The invention relates also to HIV-1 immunogens lacking a functional integrase protein.
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