- 专利标题： BCL-2/BCL-XL INHIBITORS FOR USE IN THE TREATMENT OF CANCER
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申请号： EP12739376.7申请日： 2012-01-24
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公开(公告)号： EP2668180B1公开(公告)日： 2018-08-01
- 发明人: WANG, Shaomeng , ZHOU, Haibin , CHEN, Jianfang , AGUILAR, Angelo , MEAGHER, Jennifer, Lynn , SUN, Duxin , YANG, Chao-Yie , LIU, Liu , BAI, Longchuan , MCEACHERM, Donna , STUCKEY, Jeanne , LI, Xiaoqin
- 申请人： The Regents of The University of Michigan
- 申请人地址： Office of Technology Transfer 1600 Huron Parkway, 2nd Floor Ann Arbor, MI 48109-2590 US
- 专利权人： The Regents of The University of Michigan
- 当前专利权人： The Regents of The University of Michigan
- 当前专利权人地址： Office of Technology Transfer 1600 Huron Parkway, 2nd Floor Ann Arbor, MI 48109-2590 US
- 代理机构： Studio Torta S.p.A.
- 优先权： US201161436077P 20110125
- 国际公布： WO2012103059 20120802
- 主分类号： C07D403/10
- IPC分类号： C07D403/10 ; C07D403/14 ; A61K31/496 ; A61P35/00
摘要：
Inhibitors of Bcl-2/Bcl-xL and compositions containing the same are disclosed. Methods of using the Bcl-2/Bcl-xL inhibitors in the treatment of diseases and conditions wherein inhibition of Bcl-2/Bcl-xL provides a benefit, like cancers, also are disclosed.
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