发明公开
EP2675811A1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION
审中-公开
三环吡啶衍生物，用这类化合物，它们的用途及其制造方法DRUGS
- 专利标题： TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION
- 专利标题（中）： 三环吡啶衍生物，用这类化合物，它们的用途及其制造方法DRUGS
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申请号： EP12704783.5申请日： 2012-02-16
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公开(公告)号： EP2675811A1公开(公告)日： 2013-12-25
- 发明人: WAGNER, Holger , BERTA, Daniela , FUCHS, Klaus , GIOVANNINI, Riccardo , HAMPRECHT, Wolfgang, Dieter , KONETZKI, Ingo , STREICHER, Ruediger , TRIESELMANN, Thomas
- 申请人： Boehringer Ingelheim International GmbH
- 申请人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 代理机构： Simon, Elke Anna Maria
- 优先权： EP11154898 20110217
- 国际公布： WO2012110599 20120823
- 主分类号： C07D491/04
- IPC分类号： C07D491/04 ; A61P3/06 ; A61P9/00 ; A61K31/4741
摘要：
The present invention relates to compounds defined by formula I wherein the variables R1-R8 are defined as in the description, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of cholesterol ester transfer protein (CETP) and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme.
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