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1.发明公开TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION 有权三环吡啶衍生物，用这类化合物，它们的用途及其制造方法DRUGS
公开(公告)号：EP2536733A1
公开(公告)日：2012-12-26
申请号：EP11704227.5
申请日：2011-02-17
发明人： WAGNER, Holger , BERTA, Daniela , FUCHS, Klaus , GIOVANNINI, Riccardo , HAMPRECHT, Dieter, Wolfgang , KONETZKI, Ingo , STREICHER, Ruediger , TRIESELMANN, Thomas
IPC分类号： C07D491/04 , C07D215/56 , A61K31/4741 , A61P9/00 , A61P3/06
CPC分类号： C07D491/04 , A61K31/506 , C07D215/56 , C07D491/20
摘要： The present invention relates to compounds defined by formula (I) wherein the variables R
1 -R
8 are defined as in the description, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of cholesterol ester transfer protein (CETP) and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme.-
2.发明公开TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION 有权三环吡啶衍生物，这种含药物，用途和方法FOR THEIR
公开(公告)号：EP2268644A1
公开(公告)日：2011-01-05
申请号：EP09716535.1
申请日：2009-03-02
发明人： WAGNER, Holger , BERTA, Daniela , GIOVANNINI, Riccardo , MAZZACANI, Alessandro , STREICHER, Ruediger , FUCHS, Klaus
IPC分类号： C07D493/04 , C07D493/10 , A61K31/4355 , A61P9/00
CPC分类号： C07D493/04 , C07D493/10
摘要： Compounds of formula (I) wherein the groups R1 to R8 have the meanings indicated in the description, the tautomers.the stereoisomers.the mixtures thereof and the salts thereof have valuable pharmacological properties.which make them useful for the treatment of cardiovascular and related disorders.
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3.发明授权TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION 有权三环吡啶衍生物，用这类化合物，它们的用途及其制造方法DRUGS
公开(公告)号：EP2536733B1
公开(公告)日：2014-11-26
申请号：EP11704227.5
申请日：2011-02-17
发明人： WAGNER, Holger , BERTA, Daniela , FUCHS, Klaus , GIOVANNINI, Riccardo , HAMPRECHT, Dieter, Wolfgang , KONETZKI, Ingo , STREICHER, Ruediger , TRIESELMANN, Thomas
IPC分类号： C07D491/04 , C07D215/56 , A61K31/4741 , A61P9/00 , A61P3/06
CPC分类号： C07D491/04 , A61K31/506 , C07D215/56 , C07D491/20
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4.发明公开TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION 审中-公开三环吡啶衍生物，用这类化合物，它们的用途及其制造方法DRUGS
公开(公告)号：EP2675811A1
公开(公告)日：2013-12-25
申请号：EP12704783.5
申请日：2012-02-16
发明人： WAGNER, Holger , BERTA, Daniela , FUCHS, Klaus , GIOVANNINI, Riccardo , HAMPRECHT, Wolfgang, Dieter , KONETZKI, Ingo , STREICHER, Ruediger , TRIESELMANN, Thomas
IPC分类号： C07D491/04 , A61P3/06 , A61P9/00 , A61K31/4741
CPC分类号： C07D491/048 , C07D491/107 , C07D491/18
摘要： The present invention relates to compounds defined by formula I wherein the variables R1-R8 are defined as in the description, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of cholesterol ester transfer protein (CETP) and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme.
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5.发明授权TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION 有权三环吡啶衍生物，这种含药物，用途和方法FOR THEIR
公开(公告)号：EP2268644B1
公开(公告)日：2011-08-17
申请号：EP09716535.1
申请日：2009-03-02
发明人： WAGNER, Holger , BERTA, Daniela , GIOVANNINI, Riccardo , MAZZACANI, Alessandro , STREICHER, Ruediger , FUCHS, Klaus
IPC分类号： C07D493/04 , C07D493/10 , A61K31/4355 , A61P9/00
CPC分类号： C07D493/04 , C07D493/10
摘要： Compounds of formula (I) wherein the groups R1 to R8 have the meanings indicated in the description, the tautomers.the stereoisomers.the mixtures thereof and the salts thereof have valuable pharmacological properties.which make them useful for the treatment of cardiovascular and related disorders.
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