发明公开
- 专利标题: TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS
- 专利标题(中): 三唑并吡啶化合物与PIM激酶抑制剂
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申请号: EP12716770.8申请日: 2012-02-24
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公开(公告)号: EP2678329A1公开(公告)日: 2014-01-01
- 发明人: BLAKE, James, F , DELISLE, Robert, Kirk , DE MEESE, Lisa, A. , GRAHAM, James, M. , LE HUEROU, Yvan , LYON, Michael , ROBINSON, John, E. , WALLACE, Eli, M. , WANG, Bin , XU, Rui
- 申请人: Array Biopharma, Inc.
- 申请人地址: 3200 Walnut Street Boulder, CO 80301 US
- 专利权人: Array Biopharma, Inc.
- 当前专利权人: Array Biopharma, Inc.
- 当前专利权人地址: 3200 Walnut Street Boulder, CO 80301 US
- 代理机构: Office Freylinger
- 优先权: US201161446902P 20110225
- 国际公布: WO2012154274 20121115
- 主分类号: C07D401/06
- IPC分类号: C07D401/06 ; C07D471/04 ; C07D519/00 ; A61K31/4709 ; A61P29/00
摘要:
Compounds of Formula I: in which R
1 , R
2 , R
3 , R
4 and R
10 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by PIM-1 and/or PIM-2 and/or PIM-3 kinases.
1 , R
2 , R
3 , R
4 and R
10 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by PIM-1 and/or PIM-2 and/or PIM-3 kinases.
公开/授权文献
- EP2678329B1 TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS 公开/授权日:2015-11-18
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